Metabolism of ketone bodies in pregnant sheep
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منابع مشابه
Metabolism of ketone bodies in pregnant sheep.
A combination of isotope-dilution and arteriovenous-difference techniques was used to determine the significance of ketones to energy homoeostasis in fasted pregnant ewes. 2. There was incomplete interconversion of D(-) 3-hydroxybutyrate (3HB) and acetoacetate (AcAc) and therefore neither entry rate nor oxidation of total ketone bodies could be estimated by assuming circulating ketone bodies re...
متن کاملRole of ketone bodies in perinatal myocardial energy metabolism.
Metabolic changes at around the time of birth are crucial for life. Here we review the energy utilization in the myocardium, emphasizing ketone body metabolism. Before birth, glucose and lactate are the major energy substrates for the myocardium. Long-chain fatty acids (LCFA) are normally not available as an energy substrate for the fetal heart; however, when LCFA are supplied artificially in n...
متن کاملCccxxii. Ketogenesis-antiketogenesis. v. Metabolism of Ketone Bodies
ACETOACETIC and f-hydroxybutyric acids are known to undergo two chief metabolic changes, interconversion and oxidative breakdown. The reversibility of the reaction, acetoacetic acid =,-hydroxybutyric acid, was demonstrated in liver brei by Dakin & Wakeman [1910, 1, 2] and in perfused liver by Friedmann & Maase [1910]. Furthermore, the interconversion of these ketoand hydroxy-acids, both in live...
متن کاملThe determination of ketone bodies.
Roche, J., Michel, R. & Jouan, P. (1957). Ciba Foundation Colloq. Endocrin. 10, 168. Rosenberg, I. N. (1951). J. clin. Inve8t. 30, 1. Schultz, A. L., Sandhaus, S., Demorest, H. L. & Zieve, L. (1954). J. clin. Endrocrin. 14, 1062. Sprott, W. E. & Maclagan, N. F. (1955). Biochem. J. 59,288. Taurog, A., Briggs, F. N. & Chaikoff, I. L. (1952). J. biol. Chem. 194, 655. Taurog, A., Chaikoff, I. L. & ...
متن کاملTransport of ketone bodies and lactate in the sheep ruminal epithelium by monocarboxylate transporter 1.
Due to intensive intracellular metabolism of short-chain fatty acids, ruminal epithelial cells generate large amounts of D-beta-hydroxybutyric acid, acetoacetic acid, and lactic acid. These acids have to be extruded from the cytosol to avoid disturbances of intracellular pH (pH(i)). To evaluate acid extrusion, pH(i) was studied in cultured ruminal epithelial cells of sheep using the pH-sensitiv...
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ژورنال
عنوان ژورنال: British Journal of Nutrition
سال: 1982
ISSN: 0007-1145,1475-2662
DOI: 10.1079/bjn19820140